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Amylomyces rouxii Strain CBS 438.76 Affects Cholesterol Metabolism in Cholesterol-Fed Rats OAK
FUKUSHIMA, Michihiro; HAN, Kyu-Ho; TANEICHI, Yae; IIJIMA, Setsuko; SHIMADA, Ken-ichiro; SAITOH, Katsuichi; ODA, Yuji; CHIJI, Hideyuki; SEKIKAWA, Mitsuo; 福島, 道広; 韓, 圭鎬; 島田, 謙一郎; 小田, 有二; 関川, 三男.
We examined the effects of Amylomyces rouxii, which is a mold found in some fermented foods in Indonesia, on serum cholesterol and hepatic LDL receptor mRNA in rats. Rats were fed a 0.5% cholesterol-enriched diet with (A. rouxii group) or without (control group) 30g/kg A. rouxii for 4 wk. There were no significant differences in the body weight, food intake or liver weight among the groups. However, the weight of the cecum in the A. rouxii-fed group was significantly higher than that in the control group. The cecal pH in the A. rouxii-fed group was significantly lower than that in the control group. Cecal acetic acid, propionic acid and total SCFA concentrations in the A. rouxii-fed group were significantly higher than those in the control group. The serum...
Palavras-chave: Rats; Amylomyces rouxii strain CBS 438.76; Cholesterol; Cholesterol 7α-hydroxylase mRNA; LDL receptor mRNA.
Ano: 2005 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/2911
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Correlation between the Presence of Ubiquitin Conjugated Protein Phosphatase Inhibitor 1 and Postmortem Muscle Glycogen Metabolism OAK
NYAM-OSOR, Purevdorj; SHIMADA, Kenichiro; HAN, Kyu-Ho; FUKUSHIMA, Michihiro; SEKIKAWA, Mistuo; 島田, 謙一郎; 韓, 圭鎬; 福島, 道広; 関川, 三男.
Recently, we have identified the ubiquitin conjugate, protein phosphatase inhibitor 1 (I1), from postmortem muscles. Since I1 is one of the important regulators of glycogen metabolism, the effect of this conjugate (Ub-I1) present in postmortem muscle on glycolysis was investigated. Two sample groups were distinguishable: those not containing Ub-I1 (I, n=5)and those containing Ub-I1 (II, n=27). Due to the enormous variation in ultimate pH at 48 h postmortem, the latter group was subcategorized into a IIa group showing lower or normal pH and a IIb group showing higher or dark, firm, dry meat pH. Postmortem glycolysis occurred rapidly and vigorously among group I samples. The rate and extent of postmortem glycolysis was typical in group IIa samples while it...
Palavras-chave: Ubiquitin conjugate; Protein phosphatase inhibitor 1; Glycogen; Glycolysis.
Ano: 2010 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/2961
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Effects of Anthocyanin-rich Colored Potato Flakes on Lipid Oxidation, Instrumental Color Evaluation and Sensory Characteristics in Cooked Pork Sausages OAK
JAYAWARDANA, Barana C.; YANAGIHARA, Maki; HAN, Kyu-Ho; FUKUSHIMA, Michihiro; SEKIKAWA, Mitsuo; SHIMADA, Kenichiro; 韓, 圭鎬; 福島, 道広; 関川, 三男; 島田, 謙一郎.
We investigated lipid oxidation, instrumental color evaluation, and sensory characteristics in cooked pork sausages containing anthocyanin rich colored potato (Solanum tuberosam cv. Shadow Queen) flakes (CPF). According to the thiobarbituric acid reactive substance values, addition of 2% CPF suppressed lipid oxidation (P < 0.05) by 80% compared to the control. The antioxidant activity of 2% CPF was comparable to the synthetic antioxidant butylated hydroxytoluene (0.1%) in cooked pork sausages. The L, a* values and odor, flavor, taste, texture and overall sensory quality did not significantly differ between control and 2% CPF. Overall, cooked pork sausage with 2% CPF was as acceptable to consumers as the control. Thus, the present study indicated that...
Palavras-chave: Anthocyanin; Colored potato flake; Lipid oxidation; Natural antioxidant; Pork sausage.
Ano: 2012 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/3842
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Improvement of Bread-making Quality by the Addition of Betaine OAK
葛西, 大介; 輿水, 美奈; 大庭, 潔; 長谷川, 秀樹; 名倉, 泰三; 山内, 宏昭; 韓, 圭鎬; 島田, 謙一郎; 福島, 道広.
近年,機能性が注目されているベタインを一般的な加工食品に利用することを目的に,食パン生地にベタインを高配合したときの製パン性に与える影響を検討した.まず,食パンに,ベタインをパン生地の小麦粉に対して1∼5%添加したところ,生地からのガス発生量は,ベタイン添加量に依存して減少し,ホイロ時間が増加した.特に,機能性付与を目的とした5 %の配合では,製パン性は大きく劣化し,比容積は11%低下した.次に,食パンにベタインを高濃度に配合したときの影響を低減する方法として,ミキシング前に添加する方法に対して,ミキシング後半に添加した場合の食パンの物理特性や食感に及ぼす影響を詳細に調べた.その結果,ベタイン添加によるガス発生量およびガス保持性の低下は,ミキシング後半に添加することで大幅に改善し,比容積も有意に(p<0.05)改善した.ベタイン添加による比容積の低下は,クラムの硬さと高い負の相関がみられ,クラムの硬さが有意に(p<0.05)増加するとともに,クラストの硬さが低下したが,ベタインの添加をミキシング後半とすることで,ネガティブコントロールの硬さに近い値にまで改善された.これらの結果は,食感に関する官能評価の結果とも一致していた.走査型電子顕微鏡(SEM)による生地の組織像から,ベタインを高配合すると,ミキシングおよび発酵時にグルテンネットワークの形成が十分に形成できていないこと,ミキシング後半の添加とすることで,無添加の生地に近い状態に改善する様子が観察された.以上の結果から,食パンにベタインを高配合する場合は,添加時期を遅らせることで製パン性への影響を小さくできると考えられた.
Palavras-chave: ベタイン; 製パン性; パン生地; 物性; Betaine; Bread-making quality; Dough; Physical property.
Ano: 2016 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/4520
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Porcine artery elastin preparation reduces serum cholesterol level in rats OAK
Liyanage, Ruvini; Nakamura, Yumi; Shimada, Ken-ichiro; Sekikawa, Mitsuo; Jayawardana, Barana Chaminda; Han, Kyu-Ho; Tomoko, Okada; Ohba, Kiyoshi; Takahata, Yoshihisa; Morimatsu, Fumiki; Fukushima, Michihiro; 福島, 道広; 島田, 謙一郎; 関川, 三男; 韓, 圭鎬.
The effect of porcine artery elastin on serum cholesterol level was investigated in rats fed a cholesterol-free diet. Rats were fed for 4 weeks, with a diet (ED) containing 15% casein and 5% of porcine artery elastin in comparison with a diet (CD) containing 20% casein. The total serum and non-HDL-cholesterol concentrations were lower (P<0.001) in ED-fed group than the CD-fed group at the end of the experiment. Caecal propionate concentration and Bifidobacterium and Lactobacillus population were higher (P<0.05) in ED-fed group than the CD-fed group. The results of this study suggest that porcine artery elastin could be considered as a functional dietary protein with hypocholesterolaemic ability. Favourable amino acid composition and lysine derived...
Ano: 2009 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/2681
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Potato Pulps Lowered the Serum Cholesterol and Triglyceride Levels in Rats OAK
HASHIMOTO, Naoto; ITO, Yusaku; HAN, Kyu-Ho; SHIMADA, Ken-ichiro; SEKIKAWA, Mitsuo; TOPPING, David L.; BIRD, Anthony R.; NODA, Takahiro; CHIJI, Hideyuki; FUKUSHIMA, Michihiro; 韓, 圭鎬; 島田, 謙一郎; 関川, 三男; 福島, 道広.
日本ビタミン学会、日本栄養・食糧学会共同編集
Palavras-chave: Cholesterol; Triglyceride; Potato pulps; Liver.
Ano: 2006 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/2910
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Tartary Buckwheat Sprout Powder Lowers Plasma Cholesterol Level in Rats OAK
KUWABARA, Tomoko; HAN, Kyu-Ho; HASHIMOTO, Naoto; YAMAUCHI, Hiroaki; SHIMADA, Ken-ichiro; SEKIKAWA, Mitsuo; FUKUSHIMA, Michihiro; 島田, 謙一郎; 関川, 三男; 福島, 道広; 韓, 圭鎬.
日本ビタミン学会、日本栄養・食糧学会共同編集
Palavras-chave: Bile acid; Buckwheat sprout powder; Hepatic mRNAs; Serum cholesterol; Short-chain fatty acid.
Ano: 2007 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/2909
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Trends in functional sugar research : Focus on prebiotic effects of functional sugar OAK
福島, 道広; 中村, 有美; 李, スルギ; 土平, 洋彰; 小林, 由佳; 川上, 秋桜; 岡田, 朋子; 島田, 謙一郎; 韓, 圭鎬; Fukushima, Michihiro; Nakamura, Yumi; Lee, Seulki; Tsuchihira, Hiroaki; Kobayashi, Yuka; Kawakami, Sakura; Okada, Tomoko; Shirmada, Ken-ichiro; Han, Kyu-Ho.
今回、我々は北海道十勝で生産された豆類やジャガイモ、新規作物として栽培開発を行っているチコリから難消化性糖質を分離、そのプレバイオティクス効果について検証した。 豆類では、澱粉の構造がレジスタントスターチタイプ2であり、この澱粉が加熱調理加工過程でタイプ3の老化澱粉とタンパク質の被膜が形成されることにより、消化性が低下する可能性が見い出された。その結果、ラットの盲腸内で酸発酵が増進し、短鎖脂肪酸の上昇とpHの低下が認められ、腸内環境を改善させることが明らかとなった。さらに、十勝の特産物であるジャガイモもエステル結合したリン酸基を持つ澱粉であり、レジスタントスターチタイプ2に分類される。この澱粉も加熱調理加工することによりタイプ3の老化澱粉が増加する可能性がある。このジャガイモ澱粉がラット盲腸内で短鎖脂肪酸量を増加させ、特に酪酸の総短鎖脂肪酸に対する比率の上昇は消化を刺激して、糞便重量を増加させることが明らかであり、酪酸の好材料であることが確認された。また、チコリ由来のイヌリンについても、十勝イヌリンがin vivoおよびin vitro研究で盲腸内微生物叢、特にLactobacillusおよびBifidobacteriumレベルを上昇させ、総短鎖脂肪酸濃度も増加させることが明らかとなり、従来の報告と一致していた。 以上の結果より、豆類およびジャガイモのデンプンにはレジスタントスターチの作用を有しており、また十勝で新規に栽培したチコリ由来のイヌリンにも腸内改善効果が認められ、機能性糖質としてプレバイオティクス作用を持つことが明らかとなった。
Ano: 2011 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/3321
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有色馬鈴薯の機能性 (特集 農産物の機能性評価) OAK
韓, 圭鎬; 福島, 道広.
Ano: 2014 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/4119
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「韓国の養鹿産業の現況と機能性食品の開発について」の特別講演,学術情報交換及び今後の共同研究についての打合せの実施 OAK
韓, 圭鎬.
Palavras-chave: 建国大学; 特別講演; 学術情報交換; 共同研究.
Ano: 2010 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/2872
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